Formulation And Evaluation Of Acyclovir Sodium Solid Lipid Microparticles

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Formulation and Evaluation of Solid Lipid Nanoparticles of Ramipril

Solid lipid nanoparticles are typically spherical with an average diameter between 1 and 1000 nm. It is an alternative carrier system to tradition colloidal carriers, such as, emulsions, liposomes, and polymeric micro and nanoparticles. Ramipril is an antihypertensive agent used in the treatment of hypertension. Its oral bioavailability is 28% and it is rapidly excreted through the renal route....

متن کامل

Formulation and Evaluation of Solid lipid nanoparticles: Isoniazid

Tuberculosis is an infectious disease caused by Mycobacterium Tuberculosis which attacks lungs and other parts of the body. Isoniazid is a hydrophilic drug that is having a first line antituberculosis drug. Entrapment Efficiency has been improved by preparing Solid Lipid Nanoparticles (SLNs). Two different variable Stearic acid and Tween 80 were used by using w/o/w double emulsion-solvent evapo...

متن کامل

Preparation and Evaluation of Montelukast Sodium Loaded Solid Lipid Nanoparticles

Solid lipid nanoparticles (SLNs) are an alternative carrier system used to load the drug for targeting, to improve the bioavailability by increasing its solubility, and protecting the drug from presystemic metabolism. The avoidance of presystemic metabolism is due to the nano-metric size range, so that the liver cannot uptake the drug from the delivery system and is not metabolized by the liver...

متن کامل

Formulation & Evaluation of Gemcitabine Hydrochloride Loaded Solid Lipid Nanoparticles

INTRODUCTION Gemcitabine hydrochloride is an antimetabolite (pyrimidine analog) with poor oral bioavailability (9%) due to the first pass metabolism. GEM is a water soluble drug (log p = -1.4) with a short half-life of 42 to 94 minutes (short infusions) and 245 to 638 minutes (long infusions) respectively. Extensive first pass metabolism, low bioavailability, high dosing frequency and less half...

متن کامل

Testosterone solid lipid microparticles for transdermal drug delivery. Formulation and physicochemical characterization.

PURPOSE The main objective of the study was to formulate and characterize testosterone (TS) solid lipid microparticles (SLM) to be applied as a transdermal delivery system. METHODS Testosterone SLMs were formulated using an emulsion melt homogenization method. Various types and concentrations of fatty materials, namely glyceryl monostearate (GM), glyceryl distearate (GD), stearic acid (SA) an...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: American Journal of Advanced Drug Delivery

سال: 2016

ISSN: 2321-547X

DOI: 10.21767/2321-547x.1000005